2025-10-31 14:12:55
Presenters: Blyumin-Karasik M, Colon J, Nguyen S, Rosen J
Background: Laser treatments are widely used for facial rejuvenation, targeting pigmentation and photoaging. However, post-procedure skin is vulnerable and benefits from supportive topical agents. Adaptogens are botanical-derived compounds known to improve skin resilience and repair, as a result, presenting a novel avenue for post-laser recovery enhancement. In this case series, we evaluate the cosmetic and healing benefits of a novel adaptogenic moisturizing serum (AMS) applied after facial laser procedures.
Methods: Eight patients underwent treatment with either a long-pulsed 755-nm alexandrite laser or a 1064-nm picosecond laser, with or without chemical peels. Following each session, patients applied AMS twice daily. The serum contains botanical adaptogens (e.g., curcumin, gotu kola, cordyceps, resveratrol) and hydrating agents (eg, hyaluronic acid, ceramides, squalene). Clinical efficacy was assessed through blinded evaluation of before and after photographs using a modified Griffiths photodamage photonumeric scale. Patient self-reports on tolerability and cosmetic satisfaction were also collected.
Results: All patients tolerated AMS well, with no adverse reactions. Significant improvement in skin photodamage was observed (p=0.0078), with a median photodamage score reduction of 3.5. Patients reported smoother texture, enhanced hydration, improved radiance, and expressed willingness to continue AMS use post-recovery.
Conclusion: The combination of laser treatment and AMS application resulted in enhanced aesthetic outcomes and well-tolerated skin recovery. These findings suggest that adaptogen-based topical agents may be a valuable adjunct in post-laser dermatologic care. Further prospective, controlled studies with larger sample sizes are recommended to validate these results.
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