Hot Topics in MELANOMA Evidence-based Information for Healthcare Professionals November 2025 TABLE OF CONTENTS ORIGINAL RESEARCH ................................... 4 The 31-Gene Expression Profile Test Outperforms AJCC in Stratifying Risk of Recurrence in Patients with Stage I Cutaneous Melanoma RESEARCH SUMMARY ................................ 10 31-Gene Expression Profiling for Cutaneous Melanoma: An Expert Consensus Panel EXPERT COMMENTARY .............................. 11 Takeaways from a Consensus Panel on the Use of 31-Gene Expression Profile Testing in Cutaneous Melanoma An interview with David Cotter, MD, PhD RESEARCH SUMMARY ................................ 13 The Prognostic Value of the 31-Gene Expression Profile Test in Cutaneous Melanoma: A Systematic Review and Meta-analysis MEETING HIGHLIGHTS ............................... 14 EADV 2025 Congress— Summaries of Melanoma Abstracts from the Meeting JOURNAL WATCH ...................................... 17 Highlights of Recently Published Research in Melanoma DIGITAL RESOURCE CENTER.................... 19 Resources and Events in Melanoma Research and Practice JOURNAL STAFF Managing Editor Julia E. Eckert Managing Editor Austin K. Vitelli Associate Editor Amanda Tolvaisa Associate Editor Gannon R. Vitelli Assistant Editor Michael Wong BUSINESS STAFF Director Joseph Scullin Director E. Patrick Scullin Director Emily A. Scullin Chief Medical Officer Giselle J. Geddes, MD Senior Vice President Joseph J. Morris Associate Director of Business Development Courtney McKinney Associate Director of Business Development Morgan Rinnier Associate Director of Business Development Dana Buttenbaum Data Analyst Andrew Daly Project Manager Kim Hooven Partner Patrick D. Scullin ©2025 Matrix Medical Communications. All rights reserved. This journal is a topic-specific publication that compiles and summarizes peer-reviewed, previously published content for physicians with an interest in breast cancer management. Opinions expressed by authors, contributors, and advertisers are their own and not necessarily those of Matrix Medical Communications, the editorial staff, or any member of the company’s editorial advisory boards. Matrix Medical Communications is not responsible for accuracy of dosages given in the articles printed herein. The appearance of advertisements in this journal is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality, or safety. Matrix Medical Communications disclaims responsibility for any injury to persons or property resulting from any ideas or products referred to in the articles or advertisements. Matrix Medical Communications, LLC 1595 Paoli Pike • Ste 103 • West Chester, PA 19380 • info@matrixmedcom.com Hot Topics in Melanoma [November 2025] 3
Journal of Clinical and Aesthetic Dermatology Hot Topics in Melanoma November 2025: Page 3
