Hot Topics in MELANOMA Evidence-based Information for Healthcare Professionals November 2025 INSIDE THE ISSUE ORIGINAL RESEARCH The 31-Gene Expression Profile Test Outperforms AJCC in Stratifying Risk of Recurrence in Patients with Stage I Cutaneous Melanoma RESEARCH SUMMARY 31-Gene Expression Profiling for Cutaneous Melanoma: An Expert Consensus Panel EXPERT COMMENTARY Takeaways from a Consensus Panel on the Use of 31-Gene Expression Profile Testing in Cutaneous Melanoma An interview with David Cotter, MD, PhD RESEARCH SUMMARY The Prognostic Value of the 31-Gene Expression Profile Test in Cutaneous Melanoma: A Systematic Review and Meta-analysis MEETING HIGHLIGHTS EADV 2025 Congress— Summaries of Melanoma Abstracts from the Meeting